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MATRIX METALLOPROTEINASE 14
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DeCS
Descriptor
English
:
Matrix Metalloproteinase 14
Descriptor
Spanish
:
Metaloproteinasa 14 de la Matriz
Descriptor
Portuguese
:
Metaloproteinase 14 da Matriz
Tree Number:
D08.811.277.656.300.480.525.300.500
D08.811.277.656.675.374.525.300.500
Definition
English
:
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of
PROPROTEIN CONVERTASES
such as
FURIN
.
Matrix metalloproteinase 14
plays a direct
role
in the cleavage of
proteins
in the pericellular
environment
. In addition, it can function indirectly by enzymatically activating the proprotein form of
MATRIX METALLOPROTEINASE 15.
Entry Combination - descr/qualif
English
:
Matrix Metalloproteinase 14
/
antagonists & inhibitors
use
Matrix Metalloproteinase Inhibitors
History Note
English
:
2007(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52233
Unique Identifier:
D053511
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS